Claude in Chrome extension fails to connect from Cowork cloud session (desktop app)
The claude-in-chrome browser automation tools fail to connect with a persistent "Browser extension is not connected" error, despite completing all documented setup and troubleshooting steps.
Environment:
Claude desktop app (Cowork), session running in the cloud sandbox
Chrome extension "Claude" (Claude in Chrome) — confirmed installed and enabled at chrome://extensions
Account: [monicaretzke@formalabstech.com](mailto:monicaretzke@formalabstech.com), same account used for the Cowork session
Steps taken (in order), with no change in outcome:
Confirmed extension installed and toggle enabled in chrome://extensions
Signed into claude.ai in the same Chrome browser/profile as the extension
Cleared cookies/site data for claude.ai and re-authenticated
Restarted Chrome fully (all windows)
Confirmed "Claude in Chrome" toggle is enabled in desktop app Settings → Connectors, toggled off/on
Retried the connection from the Cowork session multiple times over ~10 minutes
Expected: the Cowork session should be able to reach the browser extension (e.g., via tabs_context_mcp) once the extension is installed, enabled, and the account is signed in on both ends.
Actual: every attempt returns the same error: "Browser extension is not connected. Please ensure the Claude browser extension is installed and running..."
Note: this may be related to open issues #48806 ("Claude in Chrome + Control Chrome Failures in Cowork Mode") and #44541 ("Chrome Connection not possible with Cowork!") — the symptom matches those reports of Cowork-specific connection failures.
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