[BUG] Missing AWS Bedrock US Inference Profile for Opus 4.5
Resolved 💬 5 comments Opened Nov 25, 2025 by d1egoaz Closed Dec 22, 2025
Preflight Checklist
- [x] I have searched existing issues and this hasn't been reported yet
- [x] This is a single bug report (please file separate reports for different bugs)
- [x] I am using the latest version of Claude Code
What's Wrong?
https://docs.aws.amazon.com/bedrock/latest/userguide/inference-profiles-support.html
Bedrock currently only supports new Claude Opus 4.5 via the global inference profile global.anthropic.claude-opus-4-5-20251101-v1:0, and there are no regional profiles.
This makes it unusable for some companies.
<img width="1330" height="746" alt="Image" src="https://github.com/user-attachments/assets/eea6105c-3d34-4aa4-9fd6-d43ccc324ffb" />
➜ aws bedrock list-inference-profiles --region us-east-1 | grep Opus 9:34:24 am
"inferenceProfileName": "US Anthropic Claude 3 Opus",
"description": "Routes requests to Anthropic Cluade 3 Opus in us-east-1 and us-west-2.",
"inferenceProfileName": "US Claude Opus 4",
"description": "Routes requests to Claude Opus 4 in us-east-1, us-east-2 and us-west-2.",
"inferenceProfileName": "US Claude Opus 4.1",
"description": "Routes requests to Claude Opus 4.1 in us-east-1, us-east-2 and us-west-2.",
"inferenceProfileName": "GLOBAL Anthropic Claude Opus 4.5",
"description": "Routes requests to Anthropic Claude Opus 4.5 globally across all supported AWS Regions.",
What Should Happen?
We should have a US inference profile for Opus 4.5.
Error Messages/Logs
Steps to Reproduce
https://docs.aws.amazon.com/bedrock/latest/userguide/inference-profiles-support.html
Claude Model
Opus
Is this a regression?
I don't know
Last Working Version
_No response_
Claude Code Version
1
Platform
Anthropic API
Operating System
macOS
Terminal/Shell
Terminal.app (macOS)
Additional Information
_No response_
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